A brief history of antiphospholipid antibodies and antiphospholipid syndrome
نویسندگان
چکیده
منابع مشابه
Antiphospholipid Syndrome and Antibodies
Antiphospholipid syndrome is an acquired thrombophilia characterized by venous or artery thrombosis sometimes accompanied by thrombocytopenia in the presence of anti-phospholipid antibodies. The 14th International Antiphos-pholipid Antibodies Congress was combined with the 4th Latin American Congress on Autoimmunity and took place in Rio de Janeiro in September 2013. In this special issue we ha...
متن کامل[Antiphospholipid antibodies and antiphospholipid syndrome: diagnosis and management].
Antiphospholipid syndrome is an acquired autoimmune thrombophilia that produces significant morbidity and mortality. Its diagnosis requires the presence of antiphospholipid antibodies and clinical manifestations that include thrombotic phenomena and/or recurrent miscarriages. Antiphospholipid antibodies may be detected in many instances, including healthy subjects. Clinical manifestations are v...
متن کاملAntiphospholipid antibodies in systemic lupus erythematosus and the antiphospholipid syndrome.
The family of autoantibodies known as antiphospholipid antibodies (aPL) and the lupus anticoagulant (LA) are associated with a spectrum of clinical manifestations including life-threatening thrombosis. While our current knowledge of thrombosis is imperfect and the mere presence of aPL is imprecisely associated with clinical events, our knowledge in this area has greatly expanded in recent years...
متن کاملAntiphospholipid Antibodies and Antiphospholipid Syndrome during Pregnancy: Diagnostic Concepts
Antiphospholipid syndrome (APS) comprises of a wide spectrum of clinical and obstetric manifestations linked to the presence of antiphospholipid antibodies (aPL). APS was described in the context of lupus, and later as an isolated syndrome or primary APS. The presence of aPL, especially the lupus anticoagulant test, is associated with adverse pregnancy outcomes, such as fetal death, recurrent e...
متن کاملMultiorgan failure and antiphospholipid antibodies: the catastrophic antiphospholipid (Asherson's) syndrome.
A review of 250 patients with the catastrophic antiphospholipid (Asherson's) syndrome (CAPS) taken from the web site organized by the Europhospholipid Group (http://www.med.ub.es/MIMMUN/FORUM/CAPS.HTM) is presented in this paper. A short historical overview of the antiphospholipid syndrome (APS) is followed by a description of the "triggering" factors, associated autoimmune diseases, clinical p...
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ژورنال
عنوان ژورنال: Scientia Medica
سال: 2018
ISSN: 1980-6108,1806-5562
DOI: 10.15448/1980-6108.2018.3.31097